Jeroen Saeij

Jeroen Saeij is a distinguished full professor at the School of Veterinary Medicine at the University of California, Davis. His academic journey and professional endeavors are deeply rooted in the study of host-parasite interactions, with a particular focus on the parasite Toxoplasma gondii. Saeij's research is characterized by a multidisciplinary approach, integrating genomics, biochemistry, microscopy, immunology, and computational tools to unravel the complexities of virulence-determining genes and host factors that influence susceptibility and resistance. Saeij's work is pioneering in the field of parasitology, where he investigates the intricate interplay between Toxoplasma gondii and its mammalian hosts. His research is centered on understanding how secreted ROP and GRA effectors of Toxoplasma modulate host cells. By employing advanced techniques such as CRISPR/Cas9 loss-of-function screens, Saeij aims to identify the genes that mediate parasite fitness across various cell types, thereby contributing to a deeper understanding of infectious diseases and host-pathogen interactions. In addition to his scientific contributions, Saeij is committed to fostering an inclusive and diverse research environment. He prioritizes diversity and inclusion within his laboratory, creating a space that encourages innovative research and collaboration among a diverse group of scholars. This commitment not only enhances the quality of research but also enriches the academic experience for all members of his team. Saeij's research has significant implications for the field of infectious diseases, particularly in understanding the genetics of susceptibility to infectious diseases. His work on Toxoplasma strain differences in virulence provides valuable insights into the molecular biology and genomics of host-pathogen interactions, paving the way for potential therapeutic interventions. Through his dedication to both scientific excellence and an inclusive academic environment, Jeroen Saeij continues to make substantial contributions to the fields of parasitology and infectious disease research. His efforts not only advance our understanding of Toxoplasma gondii but also inspire the next generation of researchers in the field.