Yi Xue

Focusing on high-impact outcomes in the field of biomedical engineering, Dr. Yi Xue is an esteemed Assistant Professor at the University of California-Davis. She leads the Computational Optics for Biomedical Imaging (COBI) Lab, where her pioneering research is dedicated to advancing optical imaging technologies. Dr. Xue's work is centered around the development of customized optical microscopy systems and computational algorithms that enhance brain imaging and optogenetic stimulation, pushing the boundaries of what is possible in the study of neural circuits and neurotechnology. Dr. Xue's team has made significant strides in creating high-throughput two-photon microscopy systems. These systems are designed to image synapses through scattering brain tissue, providing unprecedented insights into the intricate workings of the brain. Additionally, her group has developed 3D holographic imaging techniques that capture neural activity with remarkable clarity and precision. This innovative approach allows for a deeper understanding of the dynamic processes occurring within neural networks. A key aspect of Dr. Xue's research is the focus on multimodal microscopy. Her work in this area involves the simultaneous imaging of fluorescence-labeled and label-free structures within the same sample. This technique offers a comprehensive view of biological specimens, facilitating a more holistic understanding of their complex structures and functions. The applications of her research are vast, with implications for non-invasive brain-computer interfaces and the broader field of neurotechnology. Dr. Xue's contributions to the field of biomedical imaging are not only technical but also transformative. By integrating computational optics with optical microscopy, she is opening new avenues for exploring the brain's mysteries. Her work is instrumental in developing tools that could revolutionize the way we understand and interact with neural circuits, ultimately contributing to advancements in brain-computer interfaces. Through her leadership at the COBI Lab, Dr. Xue is fostering an environment of innovation and collaboration. Her research is characterized by a commitment to pushing the frontiers of knowledge, with a focus on creating practical solutions that have the potential to impact both scientific understanding and clinical practice. Her dedication to excellence in research and education continues to inspire the next generation of scientists and engineers in the field of biomedical engineering.