C. Patrick Lusk

Professor C. Patrick Lusk is an esteemed Associate Professor of Cell Biology at Yale University, renowned for his extensive publications on cellular compartmentalization mechanisms. At the forefront of his research are the intricate processes involved in the biogenesis of the nuclear envelope and nuclear pore complexes (NPCs). His work is pivotal in unraveling the complexities of nuclear transport and the assembly of NPCs, which are crucial for maintaining cellular homeostasis. Dr. Lusk leads the innovative LusKing laboratory, a collaborative effort that combines cutting-edge research techniques to delve into the mysteries of cellular biology. He also co-directs the Molecular, Cellular, and Genetics Development (MCGD) graduate training track, where he mentors the next generation of scientists in the field of cell biology. His research is characterized by a multidisciplinary approach, integrating yeast cell biology, genetics, super-resolution microscopy, and proteomics. A significant aspect of Dr. Lusk's research is his focus on the function of nuclear periphery integral membrane proteins. By leveraging the simplicity and versatility of yeast as a model organism, he has made substantial contributions to our understanding of how these proteins regulate nuclear transport and contribute to the structural integrity of the nuclear envelope. His work has been instrumental in advancing the field of cell biology, providing insights that have implications for understanding various cellular processes and diseases. Dr. Lusk's expertise in super-resolution imaging has allowed him to visualize cellular structures with unprecedented clarity, offering new perspectives on the organization and dynamics of the nuclear envelope. His innovative use of proteomics has further enriched his research, enabling the identification and characterization of proteins involved in nuclear envelope biogenesis and NPC function. Throughout his career, Dr. Lusk has been committed to fostering a collaborative research environment, encouraging interdisciplinary approaches to solve complex biological questions. His dedication to education and mentorship is evident in his role as a co-director of the MCGD graduate training track, where he inspires students to pursue excellence in research and discovery. In summary, Dr. C. Patrick Lusk's contributions to the field of cell biology are marked by his pioneering research on nuclear envelope and NPC biogenesis, his leadership in the LusKing laboratory, and his commitment to training the next generation of scientists. His work continues to shape our understanding of cellular compartmentalization and its implications for health and disease.