Xandra Breakefield

Inspiring change in the area of neurological research, Xandra Breakefield is a distinguished Professor of Neurology at Harvard University. With a profound dedication to understanding the genetic mechanisms underlying diseases of the nervous system, her work has significantly advanced the field of neurology. Her research is particularly focused on brain tumors, movement disorders, and neurofibromatosis, aiming to develop innovative therapies and biomarkers that can transform patient outcomes. Professor Breakefield has been instrumental in the development of preclinical mouse models for brain tumors, which have become invaluable tools in studying the progression and treatment of these complex diseases. Her pioneering use of viral vectors for gene therapy has opened new avenues for treating tumor suppressor syndromes and other neurological disorders. Her work in this area has been recognized for its potential to revolutionize therapeutic approaches and improve the quality of life for patients. In recent years, Professor Breakefield's research has expanded to include the characterization of extracellular vesicles released by brain tumor cells. This cutting-edge work is shedding light on the communication pathways between cells and has implications for understanding the spread and treatment of glioma and glioblastoma. Her contributions to the field of neurology are not only advancing scientific knowledge but also inspiring a new generation of researchers to explore innovative solutions to complex medical challenges. Through her dedication and expertise, Xandra Breakefield continues to inspire change and drive progress in the study of diseases of the nervous system. Her work at Harvard University remains at the forefront of neurological research, offering hope and new possibilities for patients and their families worldwide.