Paola Arlotta, PhD

Paola Arlotta, PhD, has revolutionized understanding of the intricate processes that govern the development and integration of neurons within the cerebral cortex. As the Golub Family Professor of Stem Cell and Regenerative Biology at Harvard University, her pioneering research delves into the fate specification and development of projection neurons, a critical component of the brain's architecture. Her work is instrumental in elucidating how excitatory projection neurons and inhibitory interneurons are integrated into local cortical microcircuitry, a process vital for proper brain function. Dr. Arlotta's innovative approach extends to the modeling of human neuropsychiatric diseases using human brain organoids. This cutting-edge research not only enhances our comprehension of these complex disorders but also paves the way for developing novel therapeutic strategies. Her work is particularly focused on creating methods to promote neuronal regeneration in neurodegenerative diseases, offering hope for conditions that currently have limited treatment options. In addition to her research, Dr. Arlotta is deeply committed to advancing the field of neuroscience through education and mentorship. She actively engages with students and fellow researchers, fostering an environment of collaboration and innovation. Her contributions to the scientific community are widely recognized, and she continues to inspire the next generation of scientists with her dedication to understanding and improving brain health. Through her groundbreaking research and commitment to scientific excellence, Paola Arlotta is making significant strides in the quest to modulate neuronal function in psychiatric diseases affecting the cerebral cortex. Her work not only enhances our understanding of the brain's complexities but also holds promise for transformative advancements in the treatment of neurological and psychiatric conditions.