Zoran Radic

Renowned for fostering collaboration on groundbreaking research in the field of pharmaceutical sciences, Zoran Radic is an esteemed adjunct professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California-San Diego. With a distinguished career that spans both academia and research, he also serves as a Research Advisor at the University of Zagreb, Croatia. His work is pivotal in understanding the molecular structure of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), enzymes that play crucial roles in neurotransmission and are targets for therapeutic intervention in various neurological disorders. Professor Radic's research is particularly focused on the development of oxime reactivators, which are essential for counteracting the effects of organophosphate (OP) poisoning. These compounds are designed to reactivate OP-inhibited AChE and BChE, thereby restoring their normal function. His innovative approach to drug-macromolecule interactions has led to significant advancements in the field, providing insights into the structural dynamics that govern these critical biochemical processes. In addition to his work on enzyme structure and reactivation, Professor Radic has made substantial contributions to the field through the development of an intrinsic tryptophan fluorescence-based assay. This novel technique allows for the in vitro characterization of ligand interactions with AChBP, AChE, and BChE, offering a powerful tool for researchers to study these interactions in detail. His expertise in this area has not only enhanced our understanding of cholinesterase function but has also paved the way for the development of new therapeutic strategies. Throughout his career, Professor Radic has been committed to advancing the field of pharmaceutical sciences through both his research and his mentorship of the next generation of scientists. His dedication to fostering a collaborative research environment has been instrumental in driving innovation and discovery, making him a respected leader in his field.