Mei Chen

Focused on real-world applications of dermatological research, Mei Chen serves as a Professor of Dermatology at the Keck School of Medicine of USC. Her pioneering work is dedicated to unraveling the complexities of type VII collagen, a critical component in skin integrity, and its implications in various skin diseases. With a particular emphasis on recessive dystrophic epidermolysis bullosa (RDEB), a rare and debilitating genetic skin disorder, Professor Chen's research aims to translate scientific insights into tangible therapeutic solutions. Professor Chen's research portfolio is rich with studies on the effects of recombinant type VII collagen on skin wounds, offering hope for improved healing processes in patients with RDEB. Her investigations delve into the intricate signaling pathways involved in RDEB scarring, seeking to mitigate the chronic and often painful scarring that characterizes this condition. Additionally, she explores the potential of aminoglycoside-based drug therapies, evaluating their effectiveness in treating RDEB and improving patient outcomes. Beyond RDEB, Professor Chen's work extends to understanding the cellular and molecular changes associated with RDEB-related squamous cell carcinoma, a severe complication that can arise in patients with this condition. Her research not only aims to elucidate the underlying mechanisms of this cancer but also to develop strategies for early detection and intervention. With a commitment to advancing the field of dermatology, Professor Chen's contributions are instrumental in bridging the gap between basic scientific research and clinical application. Her work not only enhances our understanding of skin diseases but also paves the way for innovative treatments that improve the quality of life for individuals affected by these challenging conditions. Through her dedication and expertise, she continues to inspire the next generation of researchers and clinicians in the field of dermatology.