Kefei Yu

Professor specializing in microbiology and molecular genetics, Kefei Yu is an Associate Professor at Michigan State University. His academic journey began with a Ph.D. from the University of Southern California, which laid the foundation for his profound interest in the intricate processes of DNA recombination and repair within immune cells. Following his doctoral studies, Professor Yu gained valuable experience as a Research Associate at the Norris Cancer Center. This role honed his expertise and prepared him for his current position at Michigan State University, where he has been a pivotal figure in advancing our understanding of antigen receptor gene diversification. In his research lab, Professor Yu delves into the complexities of activation-induced cytidine deaminase (AID) regulation. His work is particularly focused on the mechanisms that generate DNA breaks during B cells class switch recombination, a critical process for immune function. Furthermore, his research investigates how repaired switch region DNA breaks may contribute to oncogenic translocations, offering insights that could have significant implications for cancer biology. Professor Yu's contributions to the field are not only advancing scientific knowledge but also paving the way for potential therapeutic strategies targeting immune-related disorders and cancers. His dedication to unraveling the molecular intricacies of DNA processes continues to inspire both his colleagues and students at Michigan State University.