Jieya Shao

Building connections between disciplines, Jieya Shao explores the intricate world of cancer biology as an Associate Professor of Medicine at Washington University School of Medicine. Her pioneering research delves into the roles of novel anticancer targets, with a particular focus on the actin-binding factor profilin-1 and the polyubiquitin-specific protein segregase p97/VCP. Through her work, she seeks to unravel the complex mechanisms by which these proteins influence cancer development and progression. Jieya Shao's research is centered on understanding how these proteins contribute to genome integrity maintenance, DNA damage response, and gene expression. By dissecting these processes, she aims to uncover vulnerabilities within cancer cells that can be exploited for the development of more effective treatments. Her work is instrumental in bridging the gap between basic science and clinical applications, offering hope for innovative therapeutic strategies. With a keen interest in chemotherapy resistance, Shao's investigations are crucial in identifying potential targets that could enhance the efficacy of existing cancer treatments. Her interdisciplinary approach not only advances our understanding of cancer biology but also paves the way for novel interventions that could significantly improve patient outcomes. Jieya Shao's contributions to the field are marked by her commitment to advancing cancer research through a comprehensive understanding of the molecular underpinnings of the disease. Her work continues to inspire and guide future research endeavors, making significant strides in the fight against cancer.