Xiaobo Wu

Professor Xiaobo Wu is an esteemed Associate Professor of Medicine in the Division of Rheumatology at Washington University School of Medicine. With a profound expertise in the intricacies of the complement system, Professor Wu's research delves into complement activation, the alternative complement pathway, and the role of neutrophils. Their scholarly contributions have been recognized in prestigious journals, including Annals of Blood, Science Immunology, and Molecular Immunology. Professor Wu's groundbreaking research has significantly advanced the understanding of the complement system's role in various pathological conditions. Notably, their work has elucidated that complement activation is a hallmark of severe SARS-CoV-2 infection, providing critical insights into the mechanisms underlying the disease's progression. Furthermore, Professor Wu has identified the pivotal role of complement activation on neutrophils, particularly in initiating endothelial adhesion and extravasation, which are crucial processes in inflammatory responses. In addition to their research endeavors, Professor Wu is dedicated to mentoring the next generation of scientists and clinicians. They are actively involved in teaching and guiding students and fellows, fostering an environment of intellectual curiosity and scientific rigor. Their commitment to education and research excellence has made them a respected figure in the field of rheumatology and immunology. Through their innovative research and dedication to education, Professor Xiaobo Wu continues to make significant contributions to the understanding of immune system dynamics, with a particular focus on the complement system and its implications in disease pathogenesis. Their work not only enhances scientific knowledge but also holds promise for the development of novel therapeutic strategies in the treatment of immune-mediated diseases.