David A. Jacobson

Dr. David A. Jacobson focuses on the intricate mechanisms that regulate pancreatic islet electrical activity and hormone secretion in response to secretagogues. As a professor in the Molecular Physiology and Biophysics department at Vanderbilt University, he delves into the cellular and molecular processes that underpin these critical physiological functions. His work aims to unravel the complexities of islet cell signaling pathways, contributing to a deeper understanding of metabolic diseases such as diabetes. Dr. Jacobson's research is pivotal in exploring how various secretagogues influence the electrical activity of pancreatic islets, ultimately affecting hormone release. By investigating these processes, he seeks to identify potential therapeutic targets for improving insulin secretion and glucose homeostasis. His laboratory employs a combination of electrophysiological techniques, molecular biology, and advanced imaging to dissect the dynamic interactions within islet cells. In addition to his research endeavors, Dr. Jacobson is committed to mentoring the next generation of scientists. He actively engages with students and postdoctoral fellows, fostering an environment of curiosity and innovation. Through his teaching and guidance, he inspires young researchers to pursue careers in biomedical sciences, emphasizing the importance of translational research in addressing pressing health challenges.