Jennifer Trowbridge

Professor Jennifer Trowbridge is involved in groundbreaking research on the intricate mechanisms of hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs) at Tufts University. As a Research Associate Professor in the Genetics, Molecular, and Cellular Biology Program, she delves into the epigenetic regulation of self-renewal processes in these critical cell types. Her work is pivotal in understanding how these cells maintain their ability to self-renew and differentiate, which is essential for both normal hematopoiesis and the development of leukemia. Professor Trowbridge's research is particularly focused on identifying the key differences in the epigenetic mechanisms that regulate HSCs and LSCs. By uncovering these distinctions, she aims to develop novel strategies for targeted leukemia therapy, potentially transforming the way this devastating disease is treated. Her work is at the forefront of cancer biology, offering hope for more effective and personalized treatment options for leukemia patients. In addition to her research on stem cell biology, Professor Trowbridge is deeply interested in the broader implications of epigenetic regulation in cancer biology. Her investigations into the bone marrow microenvironment and its role in supporting or inhibiting leukemia progression are contributing to a more comprehensive understanding of cancer biology. Her insights into the interplay between genetic and epigenetic factors in cancer development are paving the way for innovative therapeutic approaches. Professor Trowbridge's contributions to the field are not only advancing scientific knowledge but also inspiring the next generation of researchers. Her dedication to mentoring students and fostering a collaborative research environment is helping to cultivate a vibrant community of scholars committed to tackling some of the most challenging questions in genetics and cancer biology.