Matthew S. Kelly

Matthew S. Kelly is a distinguished Associate Professor of Pediatrics at Duke University, where he also holds the positions of Associate Research Professor of Global Health and Associate Research Professor in Molecular Genetics and Microbiology. His academic journey is marked by a profound commitment to understanding the intricate dynamics between the host microbiome and pathogens, particularly those that lead to infections in children. This focus is driven by a vision to innovate strategies for infection prevention through targeted microbiome modification. Dr. Kelly's research is at the forefront of pediatric infectious diseases, exploring the complex interactions between the host microbiome and invading pathogens. His work is pivotal in identifying how these interactions can be manipulated to prevent infections, with a particular emphasis on bacterial respiratory infections and the colonization processes of exogenous pathogens. His research interests extend to the upper respiratory microbiome and its role in microbial infections, aiming to unravel the mechanisms of host microbiome-pathogen interactions. Throughout his career, Dr. Kelly has been the recipient of numerous grants, underscoring the significance and potential impact of his research. His scholarly contributions are well-documented in various peer-reviewed journals, reflecting his dedication to advancing knowledge in his field. Among his ongoing projects is a study evaluating the impact of the respiratory microbiome on bacterial pathogens in infants in Botswana, a critical investigation that could inform global health strategies. Dr. Kelly is also deeply involved in research examining the association between the gut microbiome and infection risk in pediatric stem cell transplant recipients. This work is crucial in understanding how microbiome composition can influence infection susceptibility and outcomes in vulnerable populations. Additionally, his research into the role of the gut and respiratory microbiomes in COVID-19 infection susceptibility and severity in children is particularly timely, offering insights into how these microbiomes might affect disease progression and recovery. His contributions to the field of pediatrics and microbiome research are not only academic but also practical, as they hold the potential to transform infection prevention strategies in children. Dr. Kelly's work continues to inspire and guide future research directions, aiming to improve health outcomes for children worldwide.