Matthias Buck

Dr. Matthias Buck is advancing the conversation in the intricate world of cell signaling and protein-protein interactions at Case Western Reserve University School of Medicine. As a distinguished professor in multiple departments, Dr. Buck is a pivotal member of the Molecular Oncology Program, where his research delves into the complex mechanisms of small GTPases, Plexin, and Eph receptors. His work is crucial in understanding how these interactions influence both normal cellular functions and pathological conditions. Dr. Buck's research is characterized by a multidisciplinary approach, integrating structural biology, computational biology, and biophysics. This comprehensive methodology allows him to explore the nuances of cell guidance receptors and their ligands, providing insights that are vital for the development of therapeutic strategies in oncology. His expertise in transmembrane signaling and the structural dynamics of proteins positions him at the forefront of discoveries that could revolutionize our understanding of cellular communication and its implications in diseases. In addition to his research, Dr. Buck is committed to advancing education and mentorship in the field of biophysics and molecular biology. His dedication to teaching and guiding the next generation of scientists is evident in his active involvement in academic programs and his contributions to the scientific community through publications and collaborations. Through his innovative research and commitment to education, Dr. Matthias Buck continues to make significant contributions to the field of cell signaling, offering new perspectives and potential breakthroughs in the understanding and treatment of complex diseases. His work not only enhances our knowledge of cellular processes but also paves the way for novel therapeutic approaches in the fight against cancer and other diseases.