Charles Stewart

Exploring the intersection of bacteriophage infection and host cell genetic processes, Charles Stewart is a Professor of Biosciences at Rice University. His pioneering research delves into the infection mechanisms of Bacillus subtilis by bacteriophage SPO1, focusing on the significant alterations it induces in the host cell's genetic framework. Stewart's work meticulously examines the 24 genes located in the terminal redundancy of SPO1, aiming to elucidate the specific functions of their products in the disruption of host DNA and RNA synthesis. A key aspect of Stewart's research is the regulation of timing and cell division, alongside the expression of the 24 genes themselves. His studies have shed light on the intricate processes that govern these genetic changes, providing a deeper understanding of the molecular interactions between bacteriophages and their bacterial hosts. Through his research, Stewart has identified several gene products with broad-spectrum bactericidal activities, positioning them as promising candidates for the development of new antibiotics. Stewart's contributions to the field of bioengineering extend beyond his research. He is actively involved in mentoring the next generation of scientists, fostering a collaborative and innovative research environment at Rice University. His dedication to teaching and research has made him a respected figure in the academic community, inspiring students and colleagues alike. In addition to his academic pursuits, Stewart frequently collaborates with industry partners to translate his findings into practical applications. His work on antibiotic development is particularly noteworthy, as it addresses the growing global challenge of antibiotic resistance. By exploring novel bactericidal mechanisms, Stewart's research holds the potential to revolutionize the way we approach infectious diseases. Stewart's commitment to advancing the field of biosciences is evident in his numerous publications and presentations at international conferences. His research not only contributes to the scientific community's understanding of bacteriophage-host interactions but also paves the way for innovative solutions to pressing health challenges. Through his work, Charles Stewart continues to push the boundaries of bioengineering, making significant strides in the fight against bacterial infections.