Paul Gregory DeCaen

Dr. Paul Gregory DeCaen investigates emerging trends in the field of pharmacology, with a particular focus on the intricate mechanisms of ion channels and their role in human diseases. As an Associate Professor at Northwestern University, his research is pivotal in understanding how the failure of ion channel function can lead to conditions such as Autosomal Polycystic Kidney Disease (ADPKD) and epilepsy. Dr. DeCaen's lab is dedicated to unraveling the molecular and biophysical determinants that contribute to ion channel dysregulation in disease states. By employing cutting-edge techniques, his team characterizes new ion channels and explores their significance in cell physiology. This work not only advances the fundamental understanding of ion channels but also paves the way for innovative drug discovery approaches aimed at treating these complex disorders. In addition to his research on kidney diseases and epilepsy, Dr. DeCaen is deeply interested in the broader implications of ion channel function in the brain and nervous system. His work is instrumental in bridging the gap between basic biophysical research and clinical applications, offering hope for new therapeutic strategies. Through his commitment to excellence in research and education, Dr. DeCaen continues to inspire the next generation of scientists in the field of pharmacology.