Samuel Wickline

Exploring the intersection of molecular imaging and nanotechnology, Dr. Samuel Wickline is a distinguished faculty member in Molecular Pharmacology and Physiology at USF Health. He holds the prestigious Tgh Endowed Chair in Cardiovascular Medicine and serves as the Associate Dean for Cardiology at the Morsani College of Medicine. In addition, Dr. Wickline is a Professor of Cardiovascular Sciences and directs the USF Health Heart Institute, where he leads pioneering research initiatives. Dr. Wickline's academic journey began with a Bachelor of Arts in Philosophy from Pomona College in 1974, which laid a strong foundation for his analytical and critical thinking skills. He later pursued a Doctor of Medicine degree from the University of Hawaii-Manoa, graduating in 1988. His medical training provided him with a comprehensive understanding of human physiology and the complexities of cardiovascular health, which he has since applied to his research endeavors. His research interests are deeply rooted in the innovative fields of molecular imaging and nanotechnology. Dr. Wickline is particularly focused on the development of targeted peptide nanostructures designed to control gene function. This cutting-edge work has significant implications for the treatment of various diseases, offering potential pathways for more precise and effective therapies. In addition to his work on gene function control, Dr. Wickline is also involved in the creation of theranostic biocompatible perfluorocarbon nanostructures. These advanced materials are utilized for quantitative magnetic resonance imaging, providing enhanced imaging capabilities that can lead to earlier and more accurate diagnoses. His contributions to this area are paving the way for new diagnostic tools that integrate therapeutic and diagnostic processes. Furthermore, Dr. Wickline's research extends to the development of protease-activatable nanostructures for therapeutic use. These innovative structures have the potential to revolutionize treatment modalities by offering targeted delivery of therapeutic agents, minimizing side effects, and improving patient outcomes. His work in this domain exemplifies the transformative potential of nanotechnology in medicine. Dr. Wickline's dedication to advancing cardiovascular medicine through interdisciplinary research has earned him recognition as a leader in his field. His contributions continue to inspire new generations of scientists and clinicians, fostering a collaborative environment at USF Health that encourages innovation and excellence in research and education.