

Guohua An
Dr. Guohua An is a renowned researcher in the field of pharmaceutical sciences, currently serving as an Associate Professor of Pharmaceutical Sciences and Experimental Therapeutics at the University of Iowa College of Pharmacy. With a robust academic and professional background, Dr. An has made significant contributions to the understanding of pharmacokinetics and pharmacodynamics, particularly in the context of anticancer agents. Her academic journey began with a PhD that focused on the role of transporters in the pharmacokinetics and pharmacodynamics of anticancer agents, laying a strong foundation for her future research endeavors. This work has been instrumental in advancing the knowledge of how drugs are absorbed, distributed, metabolized, and excreted in the body, particularly in relation to cancer treatment. Before joining the University of Iowa, Dr. An honed her expertise in clinical drug development and PK/PD modeling and simulation at Abbott. This experience provided her with invaluable insights into the practical aspects of drug development and the application of pharmacokinetic and pharmacodynamic principles in real-world settings. Dr. An's current research interests are diverse and cutting-edge, encompassing the development of mechanistic PKPD models for both small and large molecules. She is particularly interested in model-informed drug development, which integrates modeling and simulation into the drug development process to enhance decision-making and improve outcomes. Her work in population pharmacokinetic modeling focuses on special populations, aiming to tailor drug therapies to meet the unique needs of different patient groups. Additionally, Dr. An is actively involved in quantitative systems pharmacology, a field that combines computational modeling with experimental data to understand the complex interactions within biological systems. Her research is not only advancing scientific knowledge but also has the potential to significantly impact the development of more effective and personalized therapeutic strategies. Through her dedication to research and education, Dr. Guohua An continues to contribute to the advancement of pharmaceutical sciences, inspiring both her peers and students with her innovative approach and commitment to improving healthcare outcomes.
Research Interests
Publications
, 941-951, 2019-05-07
, 45-57, 2023-09-02
, 1-11, 2022-09-12
, 1-11, 2022-09-08
, 1-10, 2022-09-13
, 113-129, 2021-03-09
, 149-163, 2019-12-02
, 161-172, 1996-06-01
, 2522-2527, 2009-07-07
, 2439-2440, 2021-09-20