Justin Cotney

Associate Professor at Genetics, University of Connecticut7 Followers

Dr. Justin L. Cotney conducts research on genetics and genome sciences, holding an Associate Professorship at UConn Health. With a keen interest in the intricate mechanisms of genetic regulation, Dr. Cotney is dedicated to advancing the understanding of genetic and developmental biology. His work often involves exploring the complexities of gene expression and the impact of genetic variations on human health. In addition to his research endeavors, Dr. Cotney serves as the Program Director for the Graduate Program in Genetics and Developmental Biology. In this role, he is committed to fostering a dynamic and supportive learning environment for graduate students, guiding them through the complexities of genetic research and development. His leadership in the program emphasizes the integration of cutting-edge research with comprehensive educational experiences. Dr. Cotney's contributions to the field are marked by his dedication to both research and education. His work not only advances scientific knowledge but also inspires the next generation of geneticists and researchers. Through his dual roles, he continues to make significant impacts in the field of genetics and genome sciences.

Research Interests

Genetic regulation genome sciences gene expression genetic variations developmental biology

Publications

1 - Genetic testing including targeted gene panel in a diverse clinical population of children with autism spectrum disorder: Findings and implications,Molecular Genetics & Genomic Medicine

Louisa Kalsner , Jennifer Twachtman‐Bassett , Kristin Tokarski , Christine Stanley , Thyde Dumont‐Mathieu , Justin Cotney , Stormy Chamberlain ,

, 171-185, 2017-12-21

2 - Neuronal overexpression of potassium channel subunit Kcnn1 prolongs survival of SOD1-linked ALS and A53T alpha-synuclein mouse models,

Maria Nagy , Justin Cotney , Wayne A. Fenton , Arthur L. Horwich ,

, 2024-10-12

3 - Abstract A05: The mitochondrial RNA polymerase is an essential downstream effector of the MYC oncoprotein,Molecular Cancer Research

Amanda Taylor , Xiaoyong Zhang , Justin Cotney , Gerald Shadel , Craig Cameron , Steven McMahon ,

, A05-A05, 2015-10-01

4 - A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development,

Andrea Wilderman , Eva D’haene , Machteld Baetens , Tara N. Yankee , Emma Wentworth Winchester , Nicole Glidden , Ellen Roets , Jo Van Dorpe , Sarah Vergult , Timothy C. Cox , Justin Cotney ,

, 2022-03-11

5 - Epigenomic and Transcriptomic Dynamics During Human Heart Organogenesis,Circulation Research

Jennifer VanOudenhove , Tara N. Yankee , Andrea Wilderman , Justin Cotney ,

, 2020-10-09

6 - Abstract 1256: Multi-focal control of mitochondrial gene expression by oncogenic MYC provides effective therapeutic targets in cancer,Cancer Research

Amanda Taylor , Clare Adams , Xiao-yong Zhang , Victoria Gennaro , Justin Cotney , Gerald Shadel , Craig Cameron , Christine Eischen , Steven McMahon ,

, 1256-1256, 2016-07-15

7 - Zebrafish models of alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye,Biology Open

Baul Yoon , Pan Yeung , Nicholas Santistevan , Lauren E. Bluhm , Kenta Kawasaki , Janina Kueper , Richard Dubielzig , Jennifer VanOudenhove , Justin Cotney , Eric C. Liao , Yevgenya Grinblat ,

, 2022-05-15

8 - Requirement ofIrf6andEsrp1/2in frontonasal and palatal epithelium to regulate craniofacial and palate morphogenesis in mouse and zebrafish,

Shannon H. Carroll , Claudio Macias Trevino , Edward B-H Li , Kenta Kawasaki , Nora Alhazmi , Shawn Hallett , Justin Cotney , Russ P. Carstens , Eric C. Liao ,

, 2020-06-14

9 - Identifying key underlying regulatory networks and predicting targets of orphan C/D boxSNORD116snoRNAs in Prader-Willi syndrome,

Rachel B. Gilmore , Yaling Liu , Christopher E. Stoddard , Michael S. Chung , Gordon G. Carmichael , Justin Cotney ,

, 2023-10-05

10 - A bipartite boundary element restricts UBE3A imprinting to mature neurons,Proceedings of the National Academy of Sciences

Jack S. Hsiao , Noelle D. Germain , Andrea Wilderman , Christopher Stoddard , Luke A. Wojenski , Geno J. Villafano , Leighton Core , Justin Cotney , Stormy J. Chamberlain ,

, 2181-2186, 2019-01-23

11 - Integration of multimodal data in the developing tooth reveals candidate regulatory loci driving human odontogenic phenotypes,Frontiers in Dental Medicine

Emma Wentworth Winchester , Alexis Hardy , Justin Cotney ,

, 2022-11-30

12 - The marked diversity of unique cortical enhancers enables neuron-specific tools by Enhancer-Driven Gene Expression,

Stefan Blankvoort , Menno P. Witter , James Noonan , Justin Cotney , Cliff Kentros ,

, 2018-03-05

13 - Mitochondrial Ribosomal Protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription,Proceedings of the National Academy of Sciences

Yulia V. Surovtseva , Timothy E. Shutt , Justin Cotney , Huseyin Cimen , Sophia Y. Chen , Emine C. Koc , Gerald S. Shadel ,

, 17921-17926, 2011-10-14

14 - Core human mitochondrial transcription apparatus is a regulated two-component system in vitro,Proceedings of the National Academy of Sciences

Timothy E. Shutt , Maria F. Lodeiro , Justin Cotney , Craig E. Cameron , Gerald S. Shadel ,

, 12133-12138, 2010-06-18

15 - Rare genetic variants inSEC24Dmodify orofacial cleft phenotypes,

Sarah W. Curtis , Jenna C. Carlson , Terri H. Beaty , Jeffrey C. Murray , Seth M. Weinberg , Mary L. Marazita , Justin L. Cotney , David J. Cutler , Michael P. Epstein , Elizabeth J. Leslie ,

, 2023-03-27

16 - Chromatin Immunoprecipitation with Fixed Animal Tissues and Preparation for High-Throughput Sequencing,Cold Spring Harbor Protocols

Justin L. Cotney , James P. Noonan ,

, pdb.prot084848, 2015-02-01

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