Yamuna Krishnan

Yamuna Krishnan is a distinguished Professor at the University of Chicago's Department of Chemistry, where she has made significant contributions to the field of nucleic acid-based molecular devices. Her pioneering research leverages the versatility of DNA as a functional imaging platform, allowing for the quantitative detection and localization of analytes within live cells. This innovative approach has opened new avenues in the realm of molecular imaging, particularly in the development of biosensors and targeted drug delivery systems. In her laboratory, Krishnan has spearheaded the creation of DNA nanomachines capable of mapping spatial and temporal pH changes, sensing reactive species, and performing simultaneous measurements of multiple analytes within specific organelles. These advancements have profound implications for understanding cellular processes and have positioned her work at the forefront of DNA nanotechnology. Her team's development of DNA nanocapsules for targeted delivery of molecular cargo further exemplifies the potential of her research in enhancing the precision of therapeutic interventions. Krishnan's contributions to the scientific community have been recognized with numerous prestigious awards, including the Infosys Prize for Physical Sciences and being named in Cell's 40 under 40 list. Her groundbreaking work has been widely published in leading scientific journals, such as Nature Nanotechnology and Annual Reviews of Biochemistry, underscoring the impact and relevance of her research in the field. Beyond her research, Krishnan is committed to advancing the field of chemistry through education and mentorship. She actively engages with students and colleagues, fostering an environment of collaboration and innovation. Her dedication to teaching and research excellence has inspired a new generation of scientists to explore the potential of DNA nanotechnology in solving complex biological challenges. Krishnan's work continues to push the boundaries of what is possible in live cell imaging and molecular imaging, with ongoing projects aimed at further refining and expanding the capabilities of DNA-based technologies. Her vision and leadership in the field have not only advanced scientific understanding but also hold promise for transformative applications in medicine and biotechnology.