Bradley Blaser

Bradley Blaser specializes in cutting-edge techniques for exploring the complexities of hematopoiesis and myeloid neoplasia. As an Assistant Professor of Hematology in the Molecular, Cellular, and Developmental Biology Program at The Ohio State University, he is at the forefront of research into the hematopoietic microenvironment and its role in regulating the clonal evolution of hematopoietic stem cells. His work spans various conditions, including homeostatic states, developmental phases, and the onset of myeloid neoplasia. Professor Blaser employs the zebrafish model system, a powerful tool in biological research, to delve into these intricate processes. His innovative approach integrates chemical genetics, genetic barcoding, lineage tracing, live cell imaging, and single-cell analyses. This multifaceted methodology allows him to dissect the dynamic changes in clonal diversity within the blood system and understand how these changes can precipitate blood cancers. His research is pivotal in advancing our understanding of blood disorders and has significant implications for developing targeted therapies. By elucidating the mechanisms that drive clonal evolution in hematopoietic stem cells, Professor Blaser's work contributes to the broader field of cancer biology and regenerative medicine. In addition to his research, Professor Blaser is committed to mentoring the next generation of scientists. He actively engages with students and colleagues, fostering a collaborative and innovative research environment. His dedication to education and research excellence has made him a respected figure in the academic community. Through his groundbreaking research and commitment to education, Bradley Blaser continues to push the boundaries of our understanding of hematopoiesis and its implications for human health. His work not only enhances our knowledge of blood cancers but also paves the way for new therapeutic strategies that could transform patient outcomes.