E. Douglas Lewandowski

E. Douglas Lewandowski, PhD, is a distinguished professor in the Division of Endocrinology, Diabetes, and Metabolism at The Ohio State University College of Medicine. With a profound dedication to understanding the complexities of cardiac health, Dr. Lewandowski's research delves into the metabolic underpinnings of impaired contractile function in diseased hearts. His work extends to exploring how altered cardiac metabolism influences peripheral organs and systemic metabolism, providing a comprehensive view of heart disease's impact on the body. Dr. Lewandowski's research is renowned for its innovative use of nuclear magnetic resonance (NMR) and stable isotope kinetics, techniques that, when combined with mass spectrometry, allow for precise quantification of metabolic flux. This approach enables the detailed analysis of pathways and single enzymes, intracellular transport rates across cellular membranes, and metabolite turnover within the intact beating heart. His work is characterized by a multidisciplinary approach that seeks to uncover the mechanistic basis of heart disease and identify potential therapeutic targets. Throughout his career, Dr. Lewandowski has been recognized for his contributions to the field of cardiac metabolism. He is a recipient of the MERIT Award from the National Heart, Lung, and Blood Institute of the NIH, which acknowledges his sustained and outstanding contributions to heart research. Additionally, he has been honored with the Established Investigator Award from the American Heart Association, further highlighting his impact on advancing our understanding of heart disease. Dr. Lewandowski's research interests are deeply rooted in the study of heart disease, isotopes, cardiac metabolism, and metabolic flux. His work continues to push the boundaries of what is known about the heart's metabolic processes, offering new insights into potential therapeutic strategies. Through his dedication and innovative research, Dr. Lewandowski remains at the forefront of efforts to combat heart disease and improve cardiovascular health. In addition to his research, Dr. Lewandowski is committed to mentoring the next generation of scientists and clinicians. His passion for teaching and guiding students and researchers is evident in his role at The Ohio State University, where he fosters an environment of inquiry and discovery. His contributions to both research and education make him a respected figure in the field of cardiac metabolism and a valuable asset to the academic community.