

Kamal D. Mehta
Dr. Kamal D. Mehta is a distinguished Professor in the Biological Chemistry and Pharmacology department at Ohio State University, where he has made significant contributions to the field of metabolic research. With a PhD from McMaster University Medical Center, Dr. Mehta has dedicated his career to unraveling the complex signaling cascades and mechanisms that regulate lipid and glucose metabolism. His research is particularly focused on the development of obesity-induced atherosclerosis, a condition that poses significant health risks worldwide. In his laboratory, Dr. Mehta employs an integrative approach that combines biochemistry, cell biology, and mouse genetics. This multidisciplinary strategy allows his team to explore how diet-sensitive protein kinase Cbeta signaling affects the size and number of adipocytes in fat tissue, particularly in response to nutrient excess. By understanding these processes, Dr. Mehta aims to shed light on the fundamental mechanisms that contribute to obesity and related metabolic disorders. A significant aspect of Dr. Mehta's research involves studying the signaling mechanisms activated by dietary cholesterol in the liver. His work seeks to elucidate how these mechanisms operate under both physiological and pathophysiological conditions. Through this research, Dr. Mehta hopes to identify how diet influences gene expression and the genetic regulation of lipid metabolism, which could lead to the discovery of novel therapeutic targets. Dr. Mehta's research is driven by the goal of developing innovative treatments for metabolic diseases such as obesity, diabetes, and atherosclerosis. By enhancing our understanding of the genetic and molecular underpinnings of these conditions, his work holds promise for improving public health outcomes. His contributions to the field have been recognized through numerous publications and collaborations with fellow researchers. Beyond his research, Dr. Mehta is committed to mentoring the next generation of scientists. He actively engages with students and colleagues, fostering an environment of curiosity and discovery. His dedication to both research and education underscores his impact on the scientific community and his ongoing efforts to advance our understanding of metabolic health.
Publications
, 2022-05-01
, 37-46, 2005-05-05
, 1076, 2022-06-01
, 229, 2023-05-18
, 385, 2014-01-01