Faculty cover photo

Joseph Adams

Joseph Adams is a distinguished Professor of Pharmacology at the University of California, San Francisco, where he has been a pivotal figure in advancing the understanding of molecular biology. He earned his Ph.D. from Pennsylvania State University, where he laid the foundation for his future research endeavors. His work primarily revolves around the intricate processes of mRNA splicing and phosphorylation, with a particular focus on the human proteome's complexity. Adams' research is centered on two families of enzymes, SRPKs and CLKs, which are integral to splicing function. These enzymes are notably over-expressed in various cancers, positioning them as promising targets for therapeutic intervention. His laboratory is renowned for employing a multidisciplinary approach, utilizing biochemical, biological, and structural techniques to unravel the molecular and cellular mechanisms by which these enzymes influence SR protein function and splicing outcomes. Throughout his career, Joseph Adams has been the recipient of numerous grants from the National Institutes of Health (NIH), supporting his groundbreaking research on splicing regulation and protein kinases. His work has significantly contributed to the scientific community's understanding of how phosphorylation impacts mRNA splicing, offering insights that could lead to novel cancer treatments. In addition to his research, Adams is a prolific author, having published extensively on topics such as RNA splicing, protein kinases, and phosphorylation mechanisms. His publications are highly regarded in the field, reflecting his commitment to advancing knowledge and fostering innovation in pharmacology. Beyond his academic and research pursuits, Joseph Adams is dedicated to mentoring the next generation of scientists. He actively engages with students and colleagues, sharing his expertise and passion for discovery. His contributions to the field have not only advanced scientific understanding but have also inspired many to pursue careers in biomedical research. Joseph Adams continues to push the boundaries of pharmacological research, with his work holding the potential to transform therapeutic approaches to cancer and other diseases. His dedication to uncovering the complexities of mRNA splicing and phosphorylation remains a driving force in his career, making him a respected leader in his field.

External Link

Publications

Share Joseph's Profile