John Golin

Adjunct Professor at Biology, Yeshiva University0 Followers

Professor at the School of Biology at Stern College, Yeshiva University, John Golin is an esteemed academic with a rich background in both teaching and research. He earned his Bachelor of Arts degree from Haverford College, followed by a Ph.D. from the University of Chicago. Further honing his expertise, Dr. Golin completed a postdoctoral fellowship at the Institute of Molecular Biology at the University of Oregon, where he delved into advanced studies in molecular biology. Dr. Golin's research interests lie at the intersection of fungal biochemistry and human genetics, with a particular emphasis on the biochemistry of fungal multidrug transport proteins and the genetics of Ashkenazi Jews. His work has been consistently supported by significant research grants from the National Institutes of Health (NIH) and the National Science Foundation (NSF), underscoring the impact and importance of his contributions to the field. Throughout his career, Dr. Golin has been recognized for his dedication to education and research. He was honored with the James Dornan Teacher of the Year award from The Catholic University of America, a testament to his commitment to excellence in teaching. His scholarly work has been published in numerous prestigious scientific journals, reflecting his ongoing contributions to the scientific community. Currently, Dr. Golin imparts his knowledge to students at Stern College, where he teaches Human Genetics. His courses are known for their rigorous approach and integration of cutting-edge research findings, providing students with a comprehensive understanding of the subject matter. Dr. Golin's passion for genetics and biochemistry is evident in his teaching, inspiring the next generation of scientists. In addition to his academic pursuits, Dr. Golin is actively involved in various professional organizations related to his field, where he collaborates with fellow researchers and contributes to the advancement of biological sciences. His commitment to both research and education continues to make a significant impact on the academic community and beyond.

Research Interests

Fungal biochemistry Multidrug transport proteins Human genetics Ashkenazi Jewish genetics

Publications

1 - Subcellular trafficking of the yeast plasma membrane ABC transporter, Pdr5, is impaired by a mutation in the N‐terminal nucleotide‐binding fold,Molecular Microbiology

Cédric Pety De Thozée , Susan Cronin , Agnieszka Goj , John Golin , Michel Ghislain ,

, 811-825, 2006-12-12

2 - An A666G mutation in transmembrane helix 5 of the yeast multidrug transporter Pdr5 increases drug efflux by enhancing cooperativity between transport sites,Molecular Microbiology

Nidhi Arya , Hadiar Rahman , Andrew Rudrow , Manuel Wagner , Lutz Schmitt , Suresh V. Ambudkar , John Golin ,

, 1131-1144, 2019-07-23

3 - The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters,Biochemical Journal

John Golin , Suresh V. Ambudkar ,

, 353-363, 2015-04-17

4 - Chemical Specificity of the PDR5 Multidrug Resistance Gene Product of Saccharomyces cerevisiae Based on Studies with Tri- n -Alkyltin Chlorides,Antimicrobial Agents and Chemotherapy

John Golin , Alisa Barkatt , Susan Cronin , George Eng , Leopold May ,

, 134-138, 2000-01-01

5 - Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element,G3 Genes|Genomes|Genetics

Hadiar Rahman , Andrew Rudrow , Joshua Carneglia , Sister Stephen Patrick Joly , Dante Nicotera , Michael Naldrett , John Choy , Suresh V Ambudkar , John Golin ,

, 357-369, 2020-01-01

6 - Cuomarin‐6‐sulfonamides May be Useful Photoaffinity‐labeling Reagents for Analyzing the Kinetics of Drug Transport and ATP Hydrolysis in ABC Multidrug Transporters,The FASEB Journal

Sarah Spierenberg , Mahantesha Basanagouda , Manohar V. Kulkarni , John Golin ,

, 2011-04-01

7 - COINCIDENT GENE CONVERSION EVENTS IN YEAST THAT INVOLVE A LARGE INSERTION,Genetics

John E Golin , S Carl Falco , Jeanne P Margolskee ,

, 1081-1094, 1986-12-01

8 - How fungal multidrug transporters mediate hyper resistance through DNA amplification and mutation,Molecular Microbiology

Atanu Banerjee , Hadiar Rahman , Rajendra Prasad , John Golin ,

, 3-15, 2022-06-06

9 - COINCIDENT GENE CONVERSION DURING MITOSIS IN SACCHAROMYCES,Genetics

John E Golin , Michael S Esposito ,

, 355-365, 1984-07-01

10 - Mitotic recombination: Mismatch correction and replicational resolution of holliday structures formed at the two strand stage in Saccharomyces,Molecular and General Genetics MGG

John E. Golin , Michael S. Esposito ,

, 252-263, 1981-10-01

11 - APDR5 -independent pathway of multi-drug resistance regulated by theSIN4 gene product,Yeast

Anne Fleckenstein , Joshua Shallom , John Golin ,

, 133-137, 1999-01-30

12 - A PDR5 ‐independent pathway of multi‐drug resistance regulated by the SIN4 gene product,Yeast

Anne Fleckenstein , Joshua Shallom , John Golin ,

, 133-137, 1999-01-30

13 - Evidence for joint genic control of spontaneous mutation and genetic recombination during mitosis inSaccharomyces,Molecular and General Genetics MGG

John E. Golin , Michael S. Esposito ,

, 127-135, 1977-01-01

14 - The yeast Pdr5p multidrug transporter: How does it recognize so many substrates?,Biochemical and Biophysical Research Communications

John Golin , Suresh V. Ambudkar , Leopold May ,

, 1-5, 2007-04-01

15 - Mitotic versus meiotic recombination in Saccharomyces cerevisiae,Current Genetics

Robert E. Malone , John E. Golin , Michael S. Esposito ,

, 241-248, 1980-04-01

16 - Robust, pleiotropic drug resistance 5 (Pdr5)-mediated multidrug resistance is vigorously maintained in Saccharomyces cerevisiae cells during glucose and nitrogen limitation,FEMS Yeast Research

Hadiar Rahman , Joshua Carneglia , Molly Lausten , Michael Robertello , John Choy , John Golin ,

, 2018-04-16

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