Laura Niedernhofer

Emphasizing adaptability and resilience in the ever-evolving field of biomedical research, Dr. Laura Niedernhofer, MD, PhD, serves as a Professor at the University of Minnesota. She is also the esteemed Director of the Institute on the Biology of Aging & Metabolism. With a profound dedication to understanding the intricacies of aging, Dr. Niedernhofer's research delves into DNA damage and repair, genome instability disorders, cellular senescence, and the broader implications of these processes on aging. Dr. Niedernhofer's work is particularly focused on unraveling the fundamental mechanisms of aging. Her innovative approach involves the use of a murine model to study a human progeroid syndrome, which is characterized by a defect in DNA repair. This model has provided invaluable insights into the aging process and has paved the way for the development of potential therapeutics aimed at mitigating age-related diseases. A pioneer in her field, Dr. Niedernhofer has significantly contributed to the discovery and development of senolytics, a novel class of drugs designed to target and eliminate senescent cells. These drugs hold promise for improving healthspan and potentially extending lifespan by addressing the cellular underpinnings of aging. Throughout her illustrious career, Dr. Niedernhofer has been recognized with numerous awards for her groundbreaking research in aging, cancer, and environmental health science. Her work not only advances scientific understanding but also holds the potential to transform therapeutic approaches to age-related conditions. Dr. Niedernhofer's commitment to research excellence is matched by her dedication to mentoring the next generation of scientists. She actively engages in collaborative projects and fosters an environment of innovation and inquiry within her research team. Her contributions continue to shape the landscape of biomedical research, offering hope for healthier aging and improved quality of life.